http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CU-34115-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-327 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-327 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C335-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D321-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C239-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D325-00 |
| filingDate | 1974-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a34c146d5657b11f19386e580e185c13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56b28685822e5242bfabf27c7a7081ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bdb81b78d9361f2d842fa5756b4c610 |
| publicationDate | 1983-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CU-34115-A |
| titleOfInvention | NEW BENCILPIRIMIDINAS |
| abstract | A process for the preparation of benzyl-pyrimidine derivatives of the general formula (I) in which R1 and R2 each independently represent a C1-3'alkyl-C1-3'alkoxy-C2-3alkenyl or alkenyloxy group. of C2-3´Z represents a nitro, amino, pyrrolo, pyrrolidino, piperidino, -NHR, -NHR5, -N (R4) (R5), -NH4COOR4, -NHCOOR4, -NHCONHR3, -NHCSNHR5, -N = N -N8R4) 2, -N8NO) 4 or -NR · -NH2, R4 represents a C1-3 alkyl or C2-3'alkenyl group R5 represents an acyl group, R3 represents a hydrogen atom or a group of C1-3alkyl or C2-3'alkenyl A represents an oxygen atom bonded to one of the cyclic nitrogen atoms and n denotes zero or 1, and its salts, the process of which comprises a) reacting a compound of the general formula (IIa) or (formula IIb) where Z represents a nitro, amino, pyrrolo, pyrrolidino, piperidino, -NHR4, -N (R4) 2´ -NHR5, -N (R4) (R5), -NR4COOR4, _NHCOOR4, -NHCONHR3, -NHCSNHR3 or -NR3NH2, the symbol R6 represents a lower alkyl group or the two symbols R6 together represent a lower alkylene group, and represents a part group and R1, R2, R3, R4 and R5 have the meaning indicated in this reinvication 1, with guanidine, or b ) reacting a compound of the general formula (III) in which X represents a chlorine or bromine atom or an alkyl mercapto, alkylsulfonyl or amino group, except that at least one of the symbols X has a meaning other than an amino group, R1 and R2 have the meaning set forth in this claim 1, and Z has the meaning set forth above in this claim, with ammonia, or c) reductively removing the substitute designated X1 in a compound of the formula general (IV) in which X1 represents a chlorine or bromine atom or a hydroxyl group, R1, R2 have the meaning set forth in this claim 1 and Z1 has the meaning set forth in this claim, or d) dia Use a compound of formula I, where Z represents an amino group, and then react the product with sodium azide, with an amine of formula NH (R4) 2 or with an alkaline sulphite, or e) treat a compound of the formula I, where Z represents a NHR4 group, with nitric acid, or f) converting the group Z2 into a compound of the general formula (Va) (Vb) 0 or (Vc) where R1 and R2 have the meaning indicated in this claim 1, and Z2, which may be the same or different in formulas Vb and Vc, represents a group convertible by reduction or hydrolysis into an amino group or a -NHR4 group, into an amino group or a group - NHR4, or g) alkylating or alkenylating the group designated with Z3 in a compound of the general formula (Ia) in which Z3 represents a group -NHR5 or -NHCOOR4 and R1, R2, R4 and R5 have the meaning indicated in this Claim 1, or h) reducing a compound of formula I, wherein Z represents a group -N (NO) R4, with Zn / CH3COOH, or b i i) subjecting a compound of formula I, where n is zero, to N-oxidation and, if desired, converting a compound of formula I obtained to a salt |
| priorityDate | 1973-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 67.