Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116fa4406381fc82bb76e8657e68788a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D271-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D285-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-433 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-433 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2014-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dc1e0632340c52db52dfedc5488325c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f65e6ac8c9c056586f63e8e785955bca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_189eddd1100625ffa30072369d8b872b |
publicationDate |
2018-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CU-24345-B1 |
titleOfInvention |
DERIVATIVES OF 1,3,4-OXADIAZOL AND 1,3,4-TIADIAZOL AS IMMUNOMODULATORS |
abstract |
<p> The present invention relates to 1,3,4-oxadiazole and 1,3,4-thiadiazole compounds as therapeutic agents capable of inhibiting the signaling pathway of programmed cell death 1 (PD1). The invention also relates to derivatives of therapeutic agents. The invention further encompasses the use of said therapeutic agents and derivatives for the treatment of disorders through immunopotentiation comprising the inhibition of the immunosuppressive signal induced due to PD-1, PD-L1 or PD-L2 and the therapies where they are used. . </p> |
priorityDate |
2013-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |