abstract |
New D-homo-estra-1,3,5 (10) -trienes substituted in position 2 of general formula (I), where R2 means a C1-C8 alkyl group, a C1-C8 alkyloxy group or a halogen atom , R3 means a hydrogen atom or a methyl group, R17 means a hydrogen atom or a fluorine atom, as well as its acceptable salts for pharmaceutical use, its production and use as pharmaceutical agents for the prophylaxis and therapy of estrogen dependent diseases on which the inhibition of 17 beta-hydroxysteroid dehydrogenase type 1 may influence. |