http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CU-20170082-A7
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22b9baa71ceef111b94d9fcf4391f1f0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-103 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2015-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5db1ffb7ca7aa41a7f9ab23313467a66 |
| publicationDate | 2017-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CU-20170082-A7 |
| titleOfInvention | TORIO COMPLEX DIRECTED TO FABRIC AND METHOD FOR PREPARATION |
| abstract | <p> The invention provides a method for the formation of a thorium complex directed to tissue, wherein said method comprises; <br /> a) forming an octadentant chelator comprising four hydroxypyridinone (HOPO) moieties substituted at position N with a C1-C3 alkyl group, and a coupling portion ending in a carboxylic acid group; <br /> b) coupling said octadentant chelator to at least one peptide or protein targeting to <br /> tissue comprising at least an amine portion by means of at least one amide coupling reagent to thereby generate a tissue targeting chelator; and <br /> c) contacting said tissue targeting chelator with an aqueous solution comprising an ion of at least one alpha-emitting thorium isotope. <br /> A method of treating a neoplastic or hyperplastic disease that it comprises the administration of said thorium complex directed to tissue, as well as the corresponding pharmaceutical complex and formulations. </p> |
| priorityDate | 2014-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.