| abstract |
The present invention relates to novel sulfonamide derivatives of formula (I) FORMULA SPACE where R1-R8 and Z are as defined in the claims, and the optical antipodes or racemates and / or salts and / or hydrates and / or solvates thereof, which are selective antagonists of bradykinin B1, to processes to produce these same compounds, to the pharmacological compositions that contain them and to their use in the therapy or prevention of painful and inflammatory conditions. |