http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CS-274511-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f8b21abc3e99d7971c9019578cd9e5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10ff9f98f91fdaa5a279dbf75585b122 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 |
filingDate | 1987-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_874c79f388c4d75ee8b5b3f1322356e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8acc0fb19f9f7003084f7c94bd502e9b |
publicationDate | 1991-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CS-274511-B1 |
titleOfInvention | Method of 1-(3,5-di-o-benzoyl-2-chloro-2-deoxy-beta-d-threo-pentafuranosile)thymine preparation |
abstract | The solution falls within the branch of preparation of pharmaceutical intermediary products. It solves a technical problem of economically advantageous production of 1-(3,5-di-0-benzoyl)-2-chlor-2-deoxy-β-D-threo-pentafuranosyl)thymine, which is the raw matter of production of 3-azido-2',3'-dideoxythimidine (AZT). The principle of the preparation procedure according to the solution consists in the fact that 1-(β-D-xylofuranosyl)thymine, obtainable from D-xylose, is across 3',5'-0-isopropylidene derivative gradually transformed to 3',5'-di-0-benzoyl-2,2'-anhydronucleoside, by whose reaction with hydrogen chloride the related compound in high overall yield and high purity is finally obtained. |
priorityDate | 1987-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.