http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CS-258270-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_83f80a3bb768dc174d7e5bb78a0f1f46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_416f16fc2895cdaade8325ef91fa8e65 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D457-12 |
| filingDate | 1986-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa2d13d0db38e38c5b47a5885ca36949 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa0cad7dc3d668d61309e6281aa6ac00 |
| publicationDate | 1988-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CS-258270-B1 |
| titleOfInvention | Process for preparing 1,6-disubstituted N- (8α-ergolinyl) -N ', N'-diethylureas |
| abstract | A new process for the production of 1, 6-disubstitutednN- (8-alpha-ergolinyl) N ', N ' -diethylureanformula I (see Annex),nwherein R 1 represents a lower alkyl groupnC 2 -C 4 and R 2 are alkylnC 1 -C 4 -alkylnthat the default known N- (l-n-alkyl-6-methyl-8-alpha-ergolinyl) -N ', N'-n-diethylurea of the formula Iidemethylatedncyanogen bromide, from the 6-cyanide obtainednof formula III is alkalinenby hydrolysis cleaves the cyano group and formednThe 6-derivative of formula IV is alkylated.nCompounds of formula I exhibitnhigh dopaminergic activity at lowntoxicity. |
| priorityDate | 1986-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 231.