| abstract |
Purification Method: 4-Carboxybutyl / triphenylphosphoniumnbromide of formula In// C6H5 / 3P / + / CH2CH2CH2CH2COOHj Br / - /nit consists in having a technical productncontaining 93 to 98% of the compound-samplenDissolve in boiling in ethanol or. \ Tn2-propanol and after cooling to 70 ° Cnto 75 ° C is added dropwise to the solutionnagitating ethyl acetate or isopropyl acetatenin 1 to 1.3 times the volumenalcohol, the suspension obtained graduallyncooled at a rate of 0.5 to 2 ° C per minutenat 0 to +5 0 after 12 to 24 hoursnstanding, the crystalline precipitate is filtered off with suction,nwashed with ethyl acetate and driednat a temperature of 90 to 110 ° C and a pressure of 0.5 ton2 kPa to yield the product of formula I. |