| abstract |
A polymeric stabilizer of emulsions of an aqueous phase in a phase of water-immiscible liquid, especially for the preparation of microparticles, consists of poly ( alpha -amino acid) derivatives based on monomer units of the general formula <IMAGE> where n = 1 to 4, X is oxygen or a -NH- group, and R is hydrogen, alkyl, hydroxyalkyl, dihydroxyalkyl or polyhydroxyalkyl, a radical derived from alkanoic or hydroxyalkanoic acid, where the alkyl has a linear, cyclic or branched aliphatic chain with 1 to 18 carbon atoms, or arylalkyl, wherein the copolymer may contain monomer units of various above described types in its chain. The preparations of spherical microparticles of starch, dextran or human serum albumine using the above stabilizer are described. |