abstract |
Process for the preparation of 1,4-dihydro-4-oxonaphthyridinenderivatives of the compound of formulanANDnCOOR'1n(!)nin which they have individual general symbolsnas defined in the subject matter of the invention and theirnsalts, are produced by cyclization of the compoundnof formula II in whichnR 1a represents a carboxyl protecting groupnfunctions and / or salts thereof;nthe resulting product is optionally cleavedna carboxyl protecting group.nThe compounds produced have strong antibacterial propertiesneffectiveness against gram-positive andnGram-negative bacteria, especially bacterianantibiotic resistant. |