http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CS-244255-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6e2627d726dce390d5c06992f9e50fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1fbbee5c50299303d569fda1fcde400 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fa1b03ef74177b8601da7fdc0bf11cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c909c95c95600c18ee205210535305f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-16 |
| filingDate | 1984-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e94d3fa732ab962faa7cf64cec3c5e62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f82d5f2b74d5248d60b8a985aca4dbdb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_697cfcd933b894f11a320b6ba9b21272 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbbadc1f7e9e37c61a17a0dbda2fdc6b |
| publicationDate | 1986-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CS-244255-B1 |
| titleOfInvention | Process for preparing 5-methylisoxazole-3-carboxylic acid amide |
| abstract | Process for the preparation of 5-methylisoxazole-3-carboxylic acid amide, which is used for the preparation of an effective chemotherapeutic agent of 3-sulfanilamido-5-methylisoxazole (sulfa- methaxazole). It can be prepared in a single-sequence manner, without isolation of the intermediates, in virtually one reactor. The acetylpyruvic acid sodium salt of sodium methoxide is known to be decomposed at a reduced temperature with sulfuric acid diluted with methanol and at the same time the reaction mixture is converted into a slightly acidic reaction in which hydroxylation with hydroxylamine hydrochloride proceeds very well. 5-Methyl-isoxazole-3-carboxylic acid methyl ester is converted to 5-methyl-isoxazole-3-carboxylic acid amide by distilling off the solvents, diluting with water and adding aqueous ammonia. |
| priorityDate | 1984-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.