http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CS-236147-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8095fcbc14f32f140efa46074f127f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0f5d3902e8f1ca5a026f5a70fc3ec47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c393111a58f760aa9747204cde77599f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-08 |
| filingDate | 1983-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aadec185bbab70eec12bcdb3e3be6832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8541f573f37bb74598a774924c7ff20d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a006e1f59e84a32e6bc11b58a362941 |
| publicationDate | 1985-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CS-236147-B1 |
| titleOfInvention | 1- [5-Chloro-2- (2-methylpiperazine methylphenylthio) benzo] - and its maleate |
| abstract | The invention is within the scope of drug synthesis.nIts subject is a new l- / 5-chloro-n-2- (2-methylphenylthio) benzyl] -4-methylpiperazinenof Formula In(51) Int. Cl. 'nOJ C 07 D 295/06,nOJ C 07 D 295/08nmaleate. The invention describes the preparation of a novelnstarting materials.nand its maleine. Formula I compound and its maleatenexhibit hypotensive efficacynof normotensive animals and are contemplatednin therapy as condition-correcting drugsnwith increased blood pressure. Latka has exceptnmild central stimulatory activitynand inhibits some microorganisms.nIt can be prepared by substitutionnby reaction of 5-chloro-2- (2-methylphenylthio) benzyl chloridenwith excess 1-methylpiperazinenin boiling chloroform. Obtained Oil «-nThe base I is converted by neutralization with acidnmaleic to crystalline hydrogen |
| priorityDate | 1983-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.