| abstract |
The present invention provides compounds of the formula (III):n or an acid addition salt thereof, wherein R 6 is chlorine, bromine, iodine, C 1 - 4 alkyl or trifluoromethyl, R 7 is hydrogen, halogen, C 1-4 alkyl or trifluoromethyl or R 6 and R 7 form a -CH=CH-CH=CH- group optionally substituted by a halogen atom or a C 1-4 alkyl or trifluoromethyl group, R 8 is hydrogen, halogen, C 1-4 alkyl or trifluoromethyl, R 9 is hydrogen, halogen, C 1-4 alkyl or trifluoromethyl, R 10 is hydrogen, methyl or fluorine and R" is amino, C 1-4 acylamino or di-substituted aminomethyleneamino provided that, at most, only two of R 7 ―R 10 are other than hydrogen and that R 7 ―R 10 are not all hydrogen when R 6 is chlorine. Also provided are pharmaceutical compositions containing compounds of the formula (III), the first medical use of compounds of the formula (III), a process for preparing such compounds and intermediates through which this process proceeds. |