http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CS-231083-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6820b51b4fc61548ff9a9c92bb1c0ede http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39ab09c03df361182ffd35e903450dc2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d2ae2820e63e91b39b3178c1903c82e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8095fcbc14f32f140efa46074f127f1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 |
| filingDate | 1982-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e649d0420547431b39566f1e76c1a58a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ba4378ea213c944a1e145eae9bc92e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2be7cf7b44386a49ce8ecf945cd3ccc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0a0d71118bddd4086943a8afb25004d |
| publicationDate | 1984-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CS-231083-B1 |
| titleOfInvention | Processing method of 4-(1-methyl-4-piperidyliden)-4,9-dihydrothieno (2,3-c)-2-benzothiepine and its hydrogen-(p-tartarate |
| abstract | 4-(1-Methyl-4-piperidylidene)- 4,9-dihydrothieno(2,3-c)-2- benzothiepin of formula I <IMAGE> and its hydrogen (+) tartrate (a novel salt) are prepared by the reaction of thieno(2,3-c)-2-benzothiepin-4(9H)- one with 1-methyl-4- piperidylmagnesium chloride in tetrahydrofuran and subsequent acid- catalysed dehydration of the resulting 4- (1-methyl-4-piperidyl)-4,9- dihydrothieno(2,3-c)-2-benzothiepin- 4-ol after removal of the simultaneously formed 7-(1-methyl-4- piperidyl)thieno(2,3-c)-2-benzothiepin -4(9H)-one. Compound I and especially its hydrogen (+) tartrate possess high antihistamine, antiserotonin, antireserpine and anticataleptic activity and are expected to find use in the therapy of migraine. |
| priorityDate | 1982-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.