http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CS-223897-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76646d99f8b5d425aec8b6bc4e333e70 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-0041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 |
filingDate | 1981-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56727db5cc4baa026e9e6995a19c3814 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_320c2df6ecf64d98fed7eb1d9cce6277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61921a7e96777cfc81c553fe3c1d1630 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84145cfbb7f8bf46ed984747cb12165f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b9f0ee39b14b8218737283c375c4097 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16eed70a7b3d132554be320eb4aaaaef |
publicationDate | 1983-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CS-223897-B2 |
titleOfInvention | Method of making the derivative of 16-amino-18,19,20-trinor-prostaglandine with ev.substituted phenyl group on the atom c 17 |
abstract | The invention relates to new 16-amino-18,19,20-trinor-prostaglandin derivatives of general formula I, having at C-17 a substituted or unsubstituted phenyl group, wherein C-15 and C-16 may have either S or R configuration, Y stands for a hydrogen atom or a lower alkyl group, W stands for a hydrogen atom, halogen atom, hydroxy group, lower alkyl or alkoxy group, and their acid addition salts. These compounds can be prepared by removing the ester group and the p-nitrobenzyloxycarbonyl protective group of a 9 alpha ,11 alpha ,15-trihydroxy-16-p-nitrobenzyloxycarbonylamido-17-phenyl-5-cis,13-tra ns-18,19,20-trinor-prostadienoic acid derivative of general formula XII-wherein C-15 and C-16 may have either S or R configuration, W is as defined above, and Y stands for a lower alkyl group-in an optional sequence with the limitation that in those compounds of general formula I where W is as defined above and Y stands for a lower alkyl group, solely the p-nitrobenzyloxycarbonyl group is removed, and the resulting product of general formula I is optionally converted with an organic or inorganic acid into a salt. The new prostaglandin derivatives of the invention have valuable therapeutical properties, and can be applied in cattle raising for estrus and birth synchronization, furthermore in the veterinary praxis for the treatment of sterility, chronic endometritis and pyometry. |
priorityDate | 1980-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 132.