http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CS-217948-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8095fcbc14f32f140efa46074f127f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_978ccf40444ebfc44eb9220436a527d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d2ae2820e63e91b39b3178c1903c82e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D337-12 |
| filingDate | 1981-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6406c448407b7335362d1be001874eb9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8163da0ebf3ea45431d3a84b47bee521 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a24ebd08aa1b78df6ec171f08143b9ad |
| publicationDate | 1983-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CS-217948-B1 |
| titleOfInvention | (6,11-Dihydrodibenzo (b, e) thiepin-11-yl) inethylamines |
| abstract | The invention relates to novel (6,11-dihydrodibenzo / b, e / thiepin-11-yl) methylaminesnwith primaryn(amino), secondary (methylamino) andntertiary (dimethylamino) amino groupnand derivatives thereof substituted in positionn4 and a methoxy group thereofnsalts with pharmaceutically acceptable inorganic saltsnor organic acids.nThe compounds of the invention have antireserpine,nlocally anesthetic and spasmolyticnefficiency, so they are usable asndrugs.nThey can be prepared by removing the appropriate onesn6,11-dihydrodibenzo [b] is thiepine-1n1-cell Curti method, ie.nconverting to chlorides and acid azides,nby rearrangement thereof by heating with atanol tonthe corresponding carbamates and then hydrolysisnof these carbamates (primary amines are obtained)nby reduction of carbamates with lithium aluminum hydriden(to obtain secondary amines) and methylationnprimary amines with formaldehydenand Ις / selina formic (obtained tertiarynamines).nThe bases obtained are converted into saltsnneutralizing with acids, preferably hydrogen chloride. |
| priorityDate | 1981-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.