http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CS-211104-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2dad08489d63a0770b7280daac0697 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d3e93c8127d73b2cbb1cf3d4042317b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf6e011c6a5445954e7766d5c2945559 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e06a4c7fa583d90bd1912f60c8513005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8095fcbc14f32f140efa46074f127f1 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D335-12 |
filingDate | 1980-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ccb6bea241ef69a1c0abed5149a3013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d6ea19137a592bc8f2ef47958dd5633 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f0413958fcc036e4352df382e4d816f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5aab30503c2461f28f1eb43c9cdb7a9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70afe799e81967c7c4e1af50b0bb4693 |
publicationDate | 1982-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CS-211104-B1 |
titleOfInvention | Aminoketone Thioxanthene Series |
abstract | The invention relates to novel 1- (2-chlorothioxanthen-9-yl)n-3-dimethylaminopropane-n- | - and its salts with pharmaceutically acceptable saltsnacids. The listed substances shownwith adequate toxicitynthe non-dramatic effects that make themnpotential neurotrophic drugs, in particularnlocal anesthetic and spasmolytic. In the examplenone possible way is describednpreparing the named base and the hydrobromide,nwhich consists of two-stage synthesis.nin the first step, the hydrochloride solution is addedncis-2-chloro-9- (3-dimethylaminopropylidene)nthioxanthene in aqueous acetic acidnwith hydrochloric acid and further with bromide.n-bromate reagent, i.e., a solution mixturenpotassium bromide and bromate. Alkalisacínto give 9-bromo-2-chloro-9- (1-hydroxy-n-3-dimethylaminopropyl) thioxanthene, whichnheating to 130 ° C cleaves hydrogen bromidenand provides the desired hydrobromide directlynproduct. |
priorityDate | 1980-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.