| abstract |
1509445 Benzodiazepines RICHTER GEDEON VEGYESZETI GYAR RT 25 June 1975 [25 June 1974] 26920/75 Heading C2C Compounds of the general formula (R 1 =halogen, CF 3 , NO 2 , NH 2 ; R 2 =H, alkyl; R 3 =NO, NH 2 , optionally substituted alkylideneamino, aralkylideneamino or acylamino) are prepared by nitrosating the 4-unsubstituted compound, optionally followed by (a) reduction and (if required) reaction with an aldehyde or acylating agent, and/or (b) alkylation. Any amino substituent(s) in the aldehyde or acylating agent may be protected during the reaction. The above compounds possess enzymeinducing properties, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier. |