abstract |
This invention stipulates beta-carbonyl compounds of formula (I) in which ring A is a pyridinyl, pyrimidinyl, morpholinyl, piperidinyl, piperazinyl, pyrrolidinyl, pyranyl, tetrahydrofuranyl, cyclohexyl, cyclopentyl or thiomorpholinyl and R1, R2 and R3 ring As described in the specification. The compounds are IKK-2 inhibitors which are useful for treating IKK-2 mediated diseases such as inflammatory diseases and cancer. |