http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CR-7481-A

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filingDate 2004-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2008-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CR-7481-A
titleOfInvention PROCEDURES FOR THE PREPARATION OF COMBRETASTATINAS
abstract The invention relates to new methods of preparing combretastatins by Wittig condensation between nitromethoxybenzaldehyde and a trimethoxybenzyl phosphonium salt or conversely a nitromethoxybenzyl phosphonium salt with trimethoxybenzaldehyde or also by a Wittig reaction on the same derivatives, in which the nitro function has been reduced to an amino group.
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