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filingDate 2016-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25b6e0b07ba2bf5372ebc529a8a5c11b
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publicationDate 2018-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CR-20180286-A
titleOfInvention CYCLIC PURINE DINUCLEOTIDES AS STING MODULATORS
abstract A compound of formula (I) wherein Y1, Y2, X1, X2, R1, R2, R3, R4, R5, R6, R8 and R9 are as defined herein; and pharmaceutically acceptable salts and tautomers of these, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments in the treatment of diseases in which modulation of STING (stimulator of interferon genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious diseases. , cancer, precancerous syndromes and as vaccine adjuvants
priorityDate 2015-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 45.