| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-84 |
| filingDate |
2010-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea355266d501f879b03813f6bb80b46e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_711d0d8dc56a047e5a02bd7b2e953521
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c63705cc55fb72fd329e6d5a06825764
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_803520f0445a35bf7e78b02506779583
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ebcfb9355a2be7724d4f2141ce2b640 |
| publicationDate |
2011-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CR-11635-A |
| titleOfInvention |
COMBRETASTATINE PREPARATION PROCEDURE |
| abstract |
The invention relates to a process for preparing a combretastatin (A): formula (I) in the form of a base or an addition salt with an acid, which consists in coupling in the presence of a base and T3P the salt of the compound (Z) -amino of formula (II) with a doubly protected L-serine derivative of formula (III) in which PG designates a petrol group of the amine function such that the compound of formula (Z) is obtained - ( Ib). |
| priorityDate |
2008-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |