| abstract |
Spirocyclic amide derivatives of formula IDondeArCH2CH2NH- represents a β-adrenoceptor binding group, processes for their preparation, pharmaceutical compositions containing them, a process for preparing said pharmaceutical compositions, their use in therapy, and intermediates for use in their preparation. pharmaceutical, specifically compounds that possess two spiro-condensed heterocyclic rings and a heterocyclic ring fused to a phenyl group. Pharmaceutical compositions comprising these compounds, which are useful for treating allergic disorders, for example for disorders of the respiratory system, or bone, dermatological, or sensory disorders. They are also useful as advertisoplastic agents. |