abstract |
Compounds that respond to the general formula (I) in which R2 represents a hydrogen, fluorine atom or a hydroxyl, cyano, trifluoromethyl, C1-6 alkyl, C1-6 alkoxy, NR8R9 group; m, n, o and p independently represent each other a number ranging from 0 to 3; it being understood that m + n <7 and that o + p <7; A represents a covalent bond, an oxygen atom, a C1-6 alkylene group or a C1-6 -O-alkylene group in which the limb represented by an oxygen atom is attached to the group R1 and the limb represented by a group alkylene is attached to the carbon of the bicycle; R1 represents an optionally substituted aryl or heteroaryl group; R3 represents a hydrogen, fluorine atom, a C1-6 alkyl group or a trifluoromethyl group; R4 represents an optionally substituted five-link heterocycle; in the base or salt state of addition to an acid. Therapeutic application. |