| abstract |
The present invention relates to imidazole derivatives of the general formula wherein R1 means halogen, lower alkyl or lower alkoxy; R2, means lower alkyl, lower hydroxyalkyl, or lower alkoxyalkyl; R3, means hydrogen, lower alkyl lower hydroxyalkyl or alkoxyalkyl; Q, means or -N = or -CH =; R4, is a group of the formula IIa or lIben where, X, Y and Z, are, independently, -CH = or -N =; and where, only one of X or Y, can be a nitrogen atom; R5 and R6 are, independently, hydrogen, lower alkyl, lower hydroxyalkyl, lower alkoxyalkyl, - (CH2) m- (CO) O- lower alkyl, - (CH2) mS (O) 2-lower alkyl, - (CH2) mC (O) NR´R ", and where, m = 0 - 3 and R 'and R" are, independently , hydrogen or lower alkyl, as well as pharmaceutically acceptable salts thereof. |