| abstract |
This invention relates to new compounds of the Formula lk, lm1, lm2, Im5, In1, In2, In5, lo1, Io2, lo5, Ip1, Ip3, pharmaceutically acceptable salts thereof and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11β-HSD1 in mammals. The invention also relates to pharmaceutical compositions of the new compounds and methods for use in reducing or controlling the production of cortisol in a cell or inhibiting the conversion of cortisone to cortisol in a cell. |