http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-6331311-A2

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filingDate 2010-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9b52a783339e98642762b7723830a1e
publicationDate 2011-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CO-6331311-A2
titleOfInvention DERIVATIVES OF N-HETEROCICLICO-6-HETEROCICLICO-IMIDAZO [1,2-ALFA] PIRIIDINA-2-CARBOXAMIDAS ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS
abstract 1. Compounds that respond to formula (I): in which: X represents a heterocyclic group optionally substituted with one or more groups independently selected from each other among the following atoms or groups: halogen, alkoxy (C1-C6) ), (C1-C6) alkyl, NRaRb, cyano, oxide, COOR8, the alkyl and alkoxy groups being optionally substituted with one or more halogen atoms; R1 represents a hydrogen atom, a halogen atom, an alkoxy group ( C1-C6), (C2-C6) alkyl, amino or NRaRb group; the alkyl and alkoxy groups may be optionally substituted with one or more halogen atoms, a hydroxy, amino or (C1-C6) alkoxy group; R2 represents a heterocyclic group, this group being optionally substituted with one or more independently selected groups. of the others among the following atoms or groups: hydroxy, (C1-C6) alkyl, (C1-C6) alkoxy, halogen, cyano, NRaRb, -CO-R5, -CO-NR6R7, -CO-O-R8, - NR9-CO-R10, the (C1-C6) alkyl and (C1-C6) alkoxy groups being optionally substituted with one or more halogen atoms or hydroxy groups, NRaRb, oxide; R3 represents a hydrogen atom, an alkyl group ( C1-C6), a (C1-C6) alkoxy group or a halogen atom; R4 represents a hydrogen atom, a (C1-C4) alkyl group, a (C1-C4) alkoxy group or a fluorine atom; R5 represents a hydrogen atom, a phenyl group or a (C1-C6) alkyl group; R6 and R7, identical or different, represent a hydrogen atom or a (C1-) alkyl group C6) or form with the nitrogen atom that takes them a cycle of 4 to 7 links optionally including another heteroatom selected from N, O or S; R8 represents a (C1-C6) alkyl group; R9 and R10, identical or different , represent a hydrogen atom or a (C1-C6) alkyl group; Ra and Rb represent, independently of each other, a hydrogen atom, a (C1-C6) alkyl group or form with the nitrogen atom to which they are attached a cycle of 4 to 7 links, which optionally includes another heteroatom chosen from N, O or S; in the form of a base or an acid addition salt.
priorityDate 2008-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 44.