http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-6270328-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
filingDate | 2010-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e4d195e7d60fe8a7e6603fd1af36440 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de4eb6b8727d4aca5dc1a7ac821c0c86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_861ae2c771b888346a764b16625853a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_180eb41816da6239ff2cf666a7468275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f78738334d6800e05c5a3b2cf3651d8 |
publicationDate | 2011-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CO-6270328-A2 |
titleOfInvention | PIRROLO DERIVATIVES [2,3] PYRIMIDINE AS INHIBITORS OF KINASE PROTEINS B |
abstract | 1. A compound of Formula (I), or a pharmaceutically acceptable salt thereof: in which: Y represents CH or N; Z1-Z2 represents a group selected from C (R6) CH, N = CH and C (R6) N; where R 6 represents hydrogen, fluoro, chloro, bromo, cyano, methyl, ethyl, difluoromethyl, trifluoromethyl or cyclopropyl; n is 0, 1 or 2; R1 represents C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4 alkoxy, C1-4 alkoxy C1-4 alkyl, C1-4 fluoroalkyl, C1-4 aminoalkyl, C1-4 hydroxyalkyl, cyano, C1 cyanoalkyl -4, C3-5 cycloalkyl, - (CH2) pNHCOCH3, - (CH2) pNHSO2CH3, - (CH2) pNHCONH2, - (CH2) pNHCONR2R3, - (CH2) pNR2R3, - (CH2) pSO2NH2, - (CH2) pSO2NR2R3 - (CH2) pCONH2, - (CH2) pCONR2R3 or - (CH2) p-R7; where p is 0, 1, 2 or 3; R2 represents hydrogen or C1-3 alkyl; R3 represents C1-3 alkyl; and R7 represents phenyl; R7 represents a 5 or 6 membered monocyclic heteroaryl ring comprising 1, 2 or 3 heteroatoms selected from O, N or S; or R7 represents a monocyclic 4, 5 or 6-membered heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from O, N or S; wherein R7 is optionally substituted with 1 or 2 substituents selected from C1-4 alkyl, trifluoromethyl, C1-4 alkoxy, fluoro, chloro, bromo, and cyano; R4 represents hydrogen, fluoro, chloro, bromo, cyano or trifluoromethyl; and R5 represents hydrogen, fluoro, chloro or bromo. |
priorityDate | 2007-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.