http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-6251358-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_859399bafbd8d83a24ec70c9755c3aae |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-10 |
| filingDate | 2009-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24ff7cc33041150e4e9cf2aa0c9bbf4c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c841e624cd702949aad3ca4742ec535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9dc7db82f1ee805ce8246187405782d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e172e3d705681370a963a6d50c57167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_355c9f06a18a423d3996548a04c8ebc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8b51b1e2a60630d1bce985f772b0bf8 |
| publicationDate | 2011-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CO-6251358-A2 |
| titleOfInvention | ASPECTATE OF ACID -CICLOPROPIL-6 |
| abstract | Aspartic acid salts of 1-cyclopropyl-6-fluoro-7- (8-methoxyimino-26-diaza-spiro [3.4] oct-6-yl) -4-oxo-1,4-dihydro- [ 1,8] naphthyridine-3-carboxylic, methods for preparing the same, and pharmaceutical antimicrobial compositions comprising the same. 1.- An aspartic acid salt of 1-cyclopropyl-6-fluoro-7- (8-methoxyimino-2,6-diaza-spiro [3.4] oct-6-yl) -4-oxo-1,4- acid dihydro- [1,8] naphthyridine-3-carboxylic represented by Formula (I): 2. The aspartic acid salt of claim 1, wherein the aspartic acid is selected from D-aspartic acid, L-aspartic acid, DL-aspartic acid or a non-racemic mixture of D-aspartic acid and L-aspartic acid. 3.- A method for preparing the aspartic acid salt of the 1-cyclopropyl-6-fluoro-7- (8-methoxyimino-2,6-diaza-spiro [3.4) oct-6-yl) -4-oxo- acid 1,4-dihydro- [1,8] naphthyridine-3-carboxylic acid of claim 1, comprising a step of reacting 1-cyclopropyl-6-fluoro-7- (8-methoxyimino-2,6-diaza) spiro [3.4] oct-6-yl) -4-oxo-1,4-dihydro- [1,8] naphthyridine-3-carboxylic acid with aspartic acid in a solvent. 4. The method of claim 3, wherein the solvent is at least one selected from the group consisting of ethyl acetate, methanol, ethanol, isopropanol, acetone, acetonitrile, hexane, isopropyl ether, and water. 5. The method of claim 3, wherein the aspartic acid is selected from D-aspartic acid, L-aspartic acid, DL-aspartic acid or a non-racemic mixture of D-aspartic acid and L-aspartic acid. 6. An antimicrobial pharmaceutical composition comprising the aspartic acid salt of 1-cyclopropyl-6-fluoro-7- (8-methoxyimino-2,6-diaza-spiro [3.4] oct-6-yl) -4- oxo-1,4-dihydro- [1,8] naphthyridine-3-carboxylic. |
| priorityDate | 2007-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.