http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-6230983-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-08 |
| filingDate | 2009-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d54b7ba9e61a0f4f1d56da6d37bd4a0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4c66ae5d901ecd0d9a620f4986f38a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eac0ea07233683a398ab500484a0ef01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfea98eae400db37de241bb0d265d0b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_124dbafc22b3ea67a22911ef8d706a09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_689cdc35155faaab34927ad5d5e89d99 |
| publicationDate | 2010-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CO-6230983-A2 |
| titleOfInvention | DERIVATIVES OF 1 - OXO - 1, 2 - DIHIDRO - ISOQINOLINA, PROCESSES FOR THE PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| abstract | 1. A compound of formula (I): where: R1 is selected from H, (C1-C6) alkyl, (C2-C6) alkenyl, (C3-C6) alkynyl, (CH2) aX-Ar and (CR101R102) aX-Ar, wherein said (C1-C6) alkyl is optionally substituted with 1, 2 or 3 groups independently selected from - (C1-C6) alkoxy, -halo, -OH, -heterocycloalkyl, (C3-C7) cycloalkyl and - NR8R9; R2 and R3 are independently selected from H, halo, (C1-C6) alkyl, (C1-C6) alkoxy and (CH2) dY; wherein said (C1-C6) alkyl is optionally substituted with 1, 2 or 3 groups independently selected from - (C1-C6) alkoxy, -halo and -OH; and wherein said (C1-C6) alkoxy is optionally substituted with 1, 2 or 3 groups independently selected from -halo and -OH; and provided that when R2 is (CH2) d-Y, R3 is selected from H, halo, (C1-C6) alkyl and (C1-C6) alkoxy; and provided that when R3 is (CH2) d-Y, R2 is selected from H, halo, (C1-C6) alkyl and (C1-C6) alkoxy; R4 and R5 are independently selected from H, (C1-C6) alkyl, (C1-C6) alkoxy, halo, CF3 and CN; R16 is selected from H, (C1-C6) alkyl and heterocycloalkyl, wherein said (C1-C6) alkyl is optionally substituted with - (C1-C6) alkoxy, -OH, -halo, - (C3-C7) cycloalkyl and - NR25R26; R17 is selected from H and (C1-C6) alkyl; or R16 and R17 together with the nitrogen atom to which they are attached form a 3 to 7 member ring, optionally containing another heteroatom selected from NR27, S and O; and optionally containing, when possible, 1 or 2 double bonds; wherein said ring is optionally substituted on the carbon with 1 or 2 substituents independently selected from - (C1-C6) alkyl, (C1-C6) alkoxy, (C2-C6) alkenyl, -OH, -CN, halo and -NR25R26, wherein said - (C1-C6) alkyl is optionally substituted with -OH. R25 and R26 are independently selected from H and (C1-C6) alkyl wherein said (C1-C6) alkyl is optionally substituted with - (C1-C6) alkoxy, -OH, -halo, - (C3-C7) cycloalkyl and - NR22R23; or R25 and R26 together with the nitrogen atom to which they are attached form a 3- to 7-membered ring, optionally containing another heteroatom selected from NR24, S and O; ... |
| priorityDate | 2007-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419559581 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID457444288 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID297 |
Total number of triples: 35.