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publicationDate 2010-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CO-6220945-A2
titleOfInvention USE OF A COMPOSITION THAT INCLUDES FORMOTEROL AND DIPROPIANATE OF BECLOMETASONE FOR THE PREVENTION AND / OR TREATMENT OF AN EXAMERATION OF ASTHMA
abstract 1. The use of a composition comprising a fixed combination of a) formoterol, a pharmaceutically acceptable salt or solvate of such salt; and b) beclomethasone dipropionate; for the manufacture of a medicament for use in the prevention and / or treatment of an exacerbation of asthma, intermittent asthma and / or episodes in chronic asthma during asthma maintenance therapy with the same composition for symptomatic relief, when necessary. 2. The use according to claim 1, wherein the molar ratio of (a) with respect to (b), calculated as formoterol with respect to beclomethasone dipropionate, is from 1: 1 to 1: 500.3.- The use according to claim 2, wherein the molar ratio of (a) with respect to (b), calculated as formoterol with respect to beclomethasone dipropionate, is from 1: 1 to 1: 100. 4. The use according to claim 3, wherein the molar ratio of (a) with respect to (b), calculated as formoterol with respect to beclomethasone dipropionate, is from 1: 3 to 1:30. 5. The use according to claim 4, wherein the molar ratio of (a) with respect to (b), calculated as formoterol with respect to beclomethasone dipropionate, is 1: 12.8. 6. The use according to claim 4, wherein the molar ratio of (a) with respect to (b), calculated as formoterol with respect to beclomethasone dipropionate, is 1: 25.6. 7. The use according to any of claims 1 to 6 wherein the first active ingredient is formoterol fumarate dihydrate. 8. The use according to any of claims 1 to 6 wherein the first active ingredient is the R-enantiomer, R formoterol or pharmaceutically acceptable salt or solvate thereof or a solvate of such salt. 9. The use according to any of the preceding claims wherein the daily dose of formoterol for adults, including maintenance therapy, can be as high as 168 micrograms, preferably 100 micrograms, and more preferably 84 micrograms and even more preferably 72 micrograms
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