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publicationDate 2010-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CO-6220935-A2
titleOfInvention 1,2,4-TRIAZOL DERIVATIVES AS MODULATORS OF MGLUR5
abstract 1. A Compound of formula (I) where R1 is selected from the group consisting of methyl, halogen and cyano; R2 is selected from the group consisting of hydrogen and fluoro; R3 is selected from the group consisting of hydrogen and C1-C3 alkyl; R4 is selected from the group consisting of hydrogen and C1-C3 alkyl; R5 is selected from the group consisting of C1-C3 alkyl and cyclopropyl; X is selected from the group consisting of: and Z is selected from the group consisting of: where R6 is selected from the group consisting of hydrogen, C1-C3 alkyl, C1-C3 haloalkyl, C1-C3 alkoxy, C1-C3 haloalkoxy and halogen; R7 is selected from the group consisting of hydrogen, C1-C3 alkyl, C1-C3 haloalkyl, C1-C3 alkoxy, C1-C3 haloalkoxy and halogen; or one of its pharmaceutically acceptable salts, hydrates, isoforms, tautomers or enantiomers.
priorityDate 2006-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 68.