http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-6210740-A2

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filingDate 2009-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80911776b3430b9a3fabc06321147f93
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publicationDate 2010-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CO-6210740-A2
titleOfInvention A COMPOSITE OF [1,2,3] BENZOTRIAZINONA SUBSTITUTED IN POSITION 3 TO IMPROVE GLUTAMATERGICAL SYNTHETIC RESPONSES
abstract This invention relates to the prevention and treatment of cerebral insufficiency including the improvement in the functioning of receptors in synapses of brain networks responsible for high-order behaviors. These brain networks participate in cognitive abilities related to memory impairment, such as those seen in a variety of dementias and imbalances in neuronal activity between different regions of the brain, as suggested in disorders of the Parkinson's disease type. , schizophrenia and affective disorders. In particular, the present invention relates to compounds useful for the treatment of said conditions and to the methods for the use of those compounds in such treatments. 1. A compound characterized in that it comprises the formula: in which: R1 and R2 are independently hydrogen, alkyl, substituted alkyl, cycloalkyl, alkynyl, substituted alkynyl, cyano, alkoxy, carboxamido, substituted carboxamido, and if R1 and R2 are alkyl , R1 and R2 can be linked with a bond or - (CH2) m- to give a cycloalkyl. R3 and R4 are independently hydrogen, alkyl, hydroxyl, alkoxy, cyano, fluoro and if R3 and R4 are alkyl, R3 and R4 can be linked with a bond or - (CH2) m- to give a cycloalkyl, Q may not be present or be hydrogen, alkyl, cycloalkyl, cycloalkenyl, alkoxy, substituted alkoxy, substituted thio, cyano, thionitrile, sulfonamide, substituted sulfonamide, substituted sulfonyl, aromatic, aromatic substituted, heteroaromatic, substituted heteroaromatic, or bicycloheteroaromatic, R5 is hydrogen, alkyl, cycloalkyl or when R6 is also alkyl, together with R6 it can form a heterocycloalkyl ring, R6 can be hydrogen, alkyl, substituted alkyl or -OR7, R7 is alkyl or, when R5 is alkyl, together with R5 it forms a ring of 5, 6 or 7 members, L can be -O-, -S-, -N = or not be, ...
priorityDate 2007-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 38.