| abstract |
1.- A 5-membered heteroaromatic ring compound, represented by the formula [I] wherein V is = N- or = CH-; W is -S- or -O-; m is 0, 1 or 2; R1 and R2 are each independently a hydrogen atom or a C1-4 alkyl group; X is -N (R4) -, -N (R5) -CO-O-, -SO2-N (R5) -, -N (R5) -SO2-, -N (R6) -SO2-N (R5) -, -CO-N (R7) -, -N (R8) -CO-, -N (R9) -CO-N (R5) -, -N (R10) - (CH2) kN (R5) -, - N (R10) - (CH2) kN (R5) -CO-, -C (R10) = NN (R7) -, -N (R10) - (CH2) k-CH (R6) -, -O-, - S- or -SO2- where k is 0 or an integer from 1 to 4, R4, R5, R6, R7, R8, R9 and R10 are each independently (1) a hydrogen atom, (2) a C1-6 alkyl group wherein the C1-6 alkyl group is optionally substituted by (a) an optionally substituted aryl group, (b) an optionally substituted heteroaromatic ring group, (c) a carboxy group, (d) a group C1-4 alkoxycarbonyl, (e) -CO-N (R15) (R16) wherein R15 and R16 are each independently, a hydrogen atom, an optionally substituted aryl group, an optionally substituted heteroaromatic ring group, a C1-6 alkyl group, wherein the C1-6 alkyl group is optionally substituted by substituents selected from the group consisting of a substituted aryl group or optionally, an optionally substituted heteroaromatic ring group, a C1-4 alkoxy group optionally substituted by an aryl group and an optionally substituted aryloxy group, or, together with the nitrogen atom attached thereto, can form an indoline ring or can form a 5- to 7-membered hetero ring optionally also containing at least one heteroatom selected from the group consisting of a nitrogen atom, an oxygen atom and a sulfur atom, (f) -N (R15) (R16) wherein R15 and R16 are as defined above, (g) -O-R17 wherein R17 is a hydrogen atom, an optionally substituted aryl group, an optionally substituted heteroaromatic ring group or a C1-6 alkyl group, wherein the group C1-6 alkyl is optionally substituted by substituents selected from the group consisting of an optionally substituted aryl group, an optionally substituted heteroaromatic ring group, a substituted C1-4 alkoxy group optionally by an aryl group and an optionally substituted aryloxy group, (h) -CO-R17 where R17 is as defined above, (i) -SO2-R17 where R17 is as defined above or (j) a cycloalkyl group from C3-7, ... |