http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-5690573-A2

Outgoing Links

Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-04
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filingDate 2006-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d78abf561b067a0876d7677a0dbdd04
publicationDate 2006-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CO-5690573-A2
titleOfInvention PROCEDURES TO CONVERT HETEROCICLIC KETONES IN AMIDO-SUBSTITUTED HETEROCICLIC COMPOUNDS
abstract 1. A process for preparing a compound of the formula (I) in which R4b and R4b 'are each independently hydrogen or (C1-C6) alkyl; X is a bond, -CH2CH2- or -C (R4C) R4C ') -, where R4c and R4c' are each independently hydrogen or (C1-C6) alkyl; R4d is hydrogen, (C1-C6) alkyl, cycloalkyl (C3-C6), or taken together with R4d 'forms a 4- to 6-membered heterocyclic ring that optionally contains an additional heteroatom selected from N, O or S; R4d' is hydrogen, (C1-C6) alkyl, or taken together with R4d forms a 4- to 6-membered heterocyclic ring that optionally contains an additional heteroatom selected from N, O or S; Z is a bond, -CH2CH2- or -C (R4e) R4e ') -, where R4e and R4e' are each independently hydrogen or (C1-C6) alkyl; and R4f and R4f 'are each independently hydrogen or (C1-C6) alkyl; or one of its pharmaceutically acceptable salts; comprising the steps of (1) reacting a compound having a formula R4d-NH-R4d 'and a cyanide source with a compound of the formula (la) to form an intermediate of the formula (lb) where Pg is a amino protecting group and R4b, R4b´, X, Z, R4d, R4d´, R4f and R4f´ are as defined above; ...
priorityDate 2003-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

Predicate Subject
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Total number of triples: 27.