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filingDate 2006-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7a36077382c1a16019d75551860481a
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publicationDate 2006-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CO-5680461-A2
titleOfInvention PHARMACEUTICAL PRODUCTS THAT INCLUDE BISPHOSPHONATES
abstract 1. A pharmaceutical product in the form of a ready-to-use solution, which comprises a package containing a bisphosphonate solution, where at least the inner surface of the package comprises a plastic material, and where the package is sterilizable by heat. 2. A product according to claim 1, in a unit dose form having a volume of about 20 milliliters to about 500 milliliters. 3. A product according to claim 1, which comprises a pH regulating agent, preferably a basic regulating agent, more preferably an organic based regulating agent. 4. A product according to claim 3, adjusted with an organic base to a physiologically acceptable pH value of pH 5.5 to 8.0 , preferably pH 6.0 to 7.5, more preferably pH 6.5.5.- A product according to claim 4, wherein the organic base is sodium citrate. 6. A product according to claim 4, wherein the organic base is sodium acetate. 7. A product according to claim 4, wherein the base is sodium or potassium phosphate. 8. A product according to claim 4, wherein the base is sodium or potassium hydroxide.12.- A pharmaceutical product, which comprises a package containing a bisphosphonate solution in the form of a ready-to-use solution, comprising: a) a unit dose of bisphosphonate ; b) an organic-based regulatory agent, and a non-ionic isotonic agent, wherein at least the inner surface of the package comprises a plastic material, and where the filled container can be heat sterilized terminally.
priorityDate 2003-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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