| abstract |
1. The present invention relates to a combination, such as a combined preparation or a pharmaceutical composition, respectively, comprising a DPP-IV inhibitor or a pharmaceutically acceptable salt thereof and a cardiovascular compound (being different from a statin) or a pharmaceutically acceptable salt thereof. The present invention also relates to the use of said combination for the prevention, delay of progression or treatment of diseases and disorders selected from the group consisting of hypertension, congestive heart failure, left ventricular hypertrophy, peripheral arterial disease, diabetes, especially diabetes mellitus type II, diabetic retinopathy, macular degeneration, cataracts, diabetic nephropathy, glomerulosclerosis, chronic renal failure, diabetic neuropathy, syndrome X, premenstrual syndrome, coronary heart disease, angina pectoris, thrombosis, atherosclerosis, myocardial infarction, transient ischemic attacks, stroke, vascular restenosis, hyperglycemia, hyperinsulinemia, hyperlipidemia, hypertriglyceridemia, insulin resistance, damaged glucose metabolism, damaged glucose tolerance conditions, damaged conditions of lack of glucose in the plasma, obesity, erectile dysfunction, skin and tissue disorders Connective status, foot ulcers and ulcerative colitis, endothelial dysfunction, and damaged vascular condescension. |