http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-5590910-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bde28565d28f037e78bf4a67776ee24 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B57-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 |
filingDate | 2004-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3dda28569321b3c26f2c2755b306f61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02a02a19757b09826fc9edcc59ae2d0d |
publicationDate | 2005-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CO-5590910-A2 |
titleOfInvention | METHOD FOR THE PREPARATION OF ESCITALOPRAM |
abstract | 1. A method for the preparation of escitalopram having the following Formula: comprising: a) .- the optical resolution of the racemic compound having the following Formula: In which X is as defined above and Z is OH or a group projection, by fractional crystallization of a diastereomeric salt thereof, or by formation and separation of the diasteromic esters thereof optionally followed by hydrolysis of the correct diasteromeric ester, so as to form a compound of the following Formula: in which X is as defined above and Z is OH or a leaving group, and when Z is OH, by converting Z into a leaving group, followed by ring closure of the compound of Formula (III) so as to form a compound of the Formula: (ll) in which X is halogen or any other group that can be converted into a cyano group, ... |
priorityDate | 2001-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.