abstract |
1. A pharmaceutical composition for the treatment of conditions in mammals, which are sensitive to COX-2 inhibition, which in combination comprises an effective amount of a COX-2 inhibitor and low dose aspirin, for simultaneous, sequential or Separated. 2.- The use of a COX-2 inhibitor for the preparation of a drug, for use in combination with low-dose aspirin for the treatment of conditions in mammals that are sensitive to COX-2.3 inhibition. method of treating a patient suffering from a condition that is sensitive to COX-2 inhibition, which comprises administering to the patient an effective amount of a COX-2 inhibitor in combination with low dose aspirin. 4. The use of aspirin. at a low dose to treat coronary ischemia syndrome, thrombosis, thromboembolism, thrombotic occlusion and reocclusion, transient ischemic attack, and first or subsequent thrombotic attack, in a patient who has the condition, when the ace Low dose pyrine is administered in combination with an effective amount of a COX-2.5 inhibitor. A composition according to claim 1, wherein the dose of aspirin is a dose in the range of about 70 mg to about 10 mg. or less (for example at least about 5 mg) per day. |