abstract |
1.- A compound of the formula (I), or a pharmaceutically acceptable salt, or an in-vivo hydrolysable ester thereof, wherein (I) C is a baryl half C'-C "Where C 'and C" are independently aryl or heteroaryl rings so that the central fragment C is represented by any of the following groups D to L: where groups D to L can be attached to rings A and B in any orientation; Where A and B are independently selected from where i) and / or ii are linked as shown in (I) through position 3 to group C and substituted in position 5 as shown in (I) by -CH2-R1a and -CH2-R1b; R2a, R2b, R3a and R3b are independently hydrogen or fluorine; R1a and R1b are independently selected from hydroxy, -Osi (tri-alkyl (1-6C) (where the 3 alkyl groups (1-6C) are independently selected from all possible alkyl groups (1-6C), -NHC (= W) R4, -OC (= O) R4, where W is O or S; ... |