| abstract |
1. A compound of Formula I, in which R1 and R2 are identical or different and are selected from a phenyl group optionally substituted with one or more halogen, (C1-C6) alkyl, (C1-C6) alkoxy, trifluoromethyl, cyano, nitro, (C1-C6) aCylsuIfonilo, (C1-C6) alkylsulfonylamino, (C1-C6) alkylcarbonyl amino, (C1-C6) alkylaminocarbonyl amino, or phenyl, (C2-C6) alkyl, cyclohexyl optionally substituted with (C1-C6) alkyl, (C1-C6) alkoxy, trifluoromethyl, cyano, or with one or more fluorine atoms, 1-naphthyl or 2-naphthyl optionally substituted with halogen, (C1- C6) alkyl, (C1-C6) alkoxy, trifluoromethyl or cyano, benzyl optionally substituted on the phenyl ring with one or more halogen, (C1-C6) alkyl, (C1-C6) alkoxy, trifluoromethyl, or cyano, a saturated or unsaturated heterocyclic radical of 5 to 10 elements optionally substituted with fluorine, (C1-C6) alkyl, (C1-C6) alkoxy, trifluoromethyl, or cyano, and a monocyclic or bicyclic heterocyclic aromatic radical 5 to 10 element cyclic optionally substituted with one or more halogen, (C1-C6) alkyl, (C1-C6) alkoxy, trifluoromethyl, cyano, nitro. or phenyl; R3 is hydrogen, (C1-C6) alkyl, benzyl, chlorine, or bromine; X where R4 is hydrogen or (C1-C6) alkyl; R5 is selected from (C2-C9) alkyl or (C7-C11) bicycloalkyl, each of which may be optionally substituted with one or more phenyl, hydroxy, benzyloxy, (C1-C6) alkoxy, (C1-C6) alkylamino, bis [(C1-C3) alkyl] -amino, 1-piperidinyl, 1-pyrrolidinyl, 2,3-dihydro-1,4-benzodioxin-2-yl, (C1-C6) hydroxy-substituted alkyl, or fluorine , benzyl, 2-phenyl-ethyl, benzocyclohexyl, or benzocyclopentyl, ... |