http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-5550435-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-46 |
filingDate | 2005-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6e98a66ecaecc786e0dbe95e9db3708 |
publicationDate | 2005-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CO-5550435-A2 |
titleOfInvention | TIAZOL COMPOUNDS FOR THE TREATMENT OF NEU-RODEGENERATIVE DISORDERS |
abstract | 1.- A compound, or its pharmaceutically acceptable salts, of the formula: in which: A is selected from the moieties -C (= O) C (= O) -, - (C = O) NR9-, -C ( = O) Z-, -C (= S) Z-, -C (= NR5) Z-, and -S (O) 2-; in which Z is a residue -CH2-, a residue -CH (OH ) -, a residue -CH (OC (= O) R11) -, a residue -CH (NR9R10) -, a residue CH (CH2 (OH)) -, a residue -CH (CH (C1-C4 alkyl) (OH)) -, or a moiety -CH (C (C1-C4 alkyl) (C1-C4 alkyl) (OH)) -; R1 is selected from a C1-C20 alkyl moiety and an -alkoxy moiety of C1-C20, a C3-C8 cycloalkyl moiety, a (C4-C8) cycloalkenyl moiety, a bi-or tricycloalkyl moiety of (C5-C11), a bi-or tricycloalkenyl moiety of (C7-C11), a moiety heterocycloalkyl (3-8 members), an aryl (C6-C14) moiety, or a heteroaryl (5-14 members) moiety, wherein said alkyl and alkoxy moieties optionally each contain one to five doubles or triples bonds, and wherein each hydrogen atom of said alkyl and alkoxy groups is optionally replaced with an atom of fluorine; in which when R1 is an alkyl or alkoxy group, R1 is optionally substituted with one to three substituents R1a, and in which when R1 is a cycloalkyl, cycloalkenyl, bi- or tricycloalkyl, bi- or tricycloalkenyl, heterocycloalkyl group , aryl, or heteroaryl, then R1 is optionally substituted with one to three substituents R1b; R1a is independently selected in each case from the moieties -OH, -C1-C6 alkyl which independently and optionally contains from one to three doubles or triples links, -C1-C6 alkoxy that independently and optionally contains one to three double or triple bonds, -Cl, -F, -Br, -I, -CN, -NO2, -NR9R10, -C (= O) NR9R10 , -S (O) nNR9R10, C (= O) R11, -S (O) nR11, -C (= O) OR12, -C3-C8 cycloalkyl, C4-C8 cycloalkenyl, -bi- or -cycloalkyl of (C5-C11), -bi- or -trichloralkenyl of (C7-C11), heterocycloalkyl (3-8 members), -aryl (C6-C14), heteroaryl (5-14 members), -aryloxy of ( C6-C14), and -heteroaryloxy (5-14 member s), wherein said alkyl, alkoxy, cycloalkyl, cycloalkenyl, bi- or tricycloalkyl, bi- or tricycloalkenyl, heterocycloalkyl, aryl, ... groups |
priorityDate | 2002-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.