| abstract |
1. Substituted 1,2,3,4-tetrahydroquinolin-2-carboxylic acid derivatives of the following formula I in the form of their physiologically compatible salts with cations or bases; if necessary, in the form of their racemates, their pure stereoisomers especially enantiomers or diastereomers, or in the form of mixtures of the stereoisomers, especially enantiomers or diastereomers, in any mixing ratio; where R1 and R2 together form respectively substituted in a single or multiple or unsubstituted form, - (CH2) n- with n = 3-10, -CH = CH-CH2-, -CH2-CH = CH, -CH = CH -CH2-CH2, -CH2-CH2-CH = CH- -CH2-CH = CH-CH2-, -CH2-CH = CH-CH2-CH2-, -CH2-CH2-CH = CH-CH2- -CH2- CH2-CH = CH-CH2-CH2-, -O-CH2-CH2-, -CH2-CH2-O- -O-CH2-CH2-CH2, -CH2-CH2-CH2-O- -CH2-O-CH2 , -CH2-CH2-O-CH2-, -CH2-O-CH2-CH2-R3 is selected from H, C1-C18 alkyl, C2-C18 alkenyl or C2-C18 alkynyl, respectively branched or unbranched, substituted simply or multiple or unsubstituted; C3-C8 cycloalkyl, saturated or unsaturated, substituted in single or multiple or unsubstituted, or of a respective heterocycle, in which at least one C atom in the ring is replaced by N, S or O; alkylaryl or alkylheteroaryl, respectively substituted in single or multiple or unsubstituted form; aryl or heteroaryl, respectively substituted in single or multiple or unsubstituted form; R4 is selected from R4a or ZR4a with Z = C1-C6 alkyl, C2-C6 alkenyl or C2-C6 alkynyl, respectively branched or unbranched, substituted in simple or multiple or unsubstituted; with R4a selected from H; C1-C12 alkyl, C2-C12 alkenyl, or C2-C12 alkynyl, ... |