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filingDate 2000-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39a49ff69eacc83038fddc9f862e2f42
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publicationDate 2002-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CO-5180634-A1
titleOfInvention SULFONAMIDS REPLACED WITH NAFTILO
abstract 1. Compounds of general formula (I), <EMI FILE = "00054512_1" ID = "1" MFI = JPEG> in which R1 is hydrogen or alkanoyl (C1.C6), R2 is alkyl (C1-C6), which is substituted with a saturated heterocyclic group of 5 to 6 elements with one to three heteroatoms of the O, S, or, N series that may also eventually be linked by the N atom, oR2 is a group of formulas <EMI FILE = "00054512_2 "ID =" 2 "IMF = JPEG> R4 represents (C1-C6) alkyl, which may eventually be substituted with amino, (C1-C6) alkoxylamino, halogen or a saturated heterocyclic group of 5 to 6 elements with one to three O, S, or N series heteroatoms, which may also eventually be linked by the N atom, an aromatic heterocyclic group of 5 to 6 elements with one to three heteratoms of the O, S or N series, cycloalkyl (C3 - C7), (C1-C6) alkoxycarbonyl or -NR9R10, in which R9 and R10 are the same or different and each represents hydrogen, (C1-C6) alkyl, which may eventually be tar substituted with one to three substituents selected from halogen, hydroxy, carboxyl and (C1-C6) alkoxy, (C7-C20) alkyl or phenyl, which is optionally substituted with carboxyl, oR9 and R10 together with the nitrogen atom to which they are together, they form a saturated or unsaturated ring with up to 7 carbon atoms whose carbon atoms in the ring may eventually be replaced by 1 or 2 moieties selected from the group consisting of O, S, S = O, C = O and N-R11 , where R11 represents hydrogen or (C1-C6) alkyl, R5 represents (C1-C8) alkyl, which may eventually be substituted with -CF3, -C2F5 or with a saturated heterocyclic group of 5 to 6 elements with one to three heteroatoms of the series O, S, or N, which may also be linked by the atom of N, cycloalkyl (C3-C7) or -NR12R13, in which R12 and R13 are the same or different and each represents alkyl (C1 - C6) - 2 -R12 and R13 together with the nitrogen atom to which they are together, they form a saturated or unsaturated ring with up to 6 carbon atoms, whose carbon atoms in the ring may eventually be replaced by 1 or 2 moieties selected from the group consisting of O, S, S = O, C = O and N - R14, in which R14 represents hydrogen or (C1-C6) alkyl, R6 represents R15 -OCH2CH2OCH2CH2-, where R15 is (C1-C6) alkyl, represents a saturated heterocyclic group of 5 to 6 elements with one to three heteroatoms of the series O, S, or N, which may also be linked by the N atom, and eventually substituted with (C1-C6) alkyl or represents (C1-C6) alkyl, which may eventually be substituted with hydroxy, alkoxy (C1-C6), a saturated, unsaturated or aromatic heterocyclic group of 5 to 6 elements, with one to three heteroatoms of the O, S, or N series, which may also eventually be linked by the N, R7 atom is (C1-C6) alkyl, R8 is amino, mono or C1-C6 dialkyl amino, oR1 and R2 together with the nitrogen atom to which they are attached they form a saturated ring with up to 6 carbon atoms, whose carbon atoms in the ring may eventually be replaced by 1 or 2 moieties selected from the group consisting of O, S, S = O, C = O and N-R16, in which R16 represents hydrogen, (C1-C6) alkyl, which may eventually be substituted with halogen, or (C1-C6) alkanoyl, which may eventually be substituted with 1 to 3 halogen atoms, and where the ring can be condensed with a phenyl ring, oR1 and R2 can both be hydrogen, if A or D represents (C1-C6) alkyl sulfonyl, R3 represents <EMI FILE = "00054512_3" ID = "3" IMF = JPEG> in which R17 represents (C1-C6) alkyl, which is optionally substituted once or three times the same or differently with hydroxy, halogen or (C1-C4) alkoxy carbonyl, A, D, E and G are the same or different and represent hydrogen, halogen, nitro, cyano, hydroxy, carboxyl, trifluoromethyl, trifluoromethoxy or (C1-C) alkyl 6), (C1-C6) alkoxy, (C1-C6) alkanoyloxy, (C1-C6) alkoxycarbonyl (C1-C6) alkyl sulfonyl, and salts thereof.
priorityDate 1999-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 72.