http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-5160249-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb66d9373d09efad73c142762f6dfb00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C63-331 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-19 |
| filingDate | 2000-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df0b16f360075534cfcc3fe8185c88d6 |
| publicationDate | 2002-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CO-5160249-A1 |
| titleOfInvention | PROCEDURE TO PREPARE DERIVATIVES OF BIFENIL-2- CARBOXYL ACID |
| abstract | Process for preparing biphenyl-2-carboxylic acid derivatives of general formula (I) <EMI FILE = "00012756_1" ID = "1" IMF = JPEG> in which R1 and R2 which may be identical or different, represent hydrogen, alkyl C1-C6, which may be optionally substituted with halogen, C1-C6 alkoxy, C1-C6 acyl, C1-C6 alkoxycarbonyl, COOH, phenyl, benzyl, halogen, hydroxy, nitro or amino, or wherein R1 and R2 together with the adjacent carbon atoms of the phenyl ring form a 5 or 6 membered carbocyclic group, saturated or unsaturated, which may be optionally substituted with C1-C4 alkyl, halogen, COOH, phenyl or hydroxy; characterized in that a derivative of (2-oxazolinyl) -2-biphenyl of general formula (IV) <EMI FILE = "00012756_2" ID = "2" IMF = JPEG> in which R1 and R2 are as defined above and ROX represents an oxazolin group- 2-yl, which may be optionally mono-, di-, tri- or tetra-substituted with one or more of the C1-C6 alkyl groups, which may be optionally substituted with halogen, hydroxy or C1-C4 alkoxy, C1-C6 alkoxy, phenyl, which may be optionally substituted with C1-C4 alkyl, C1-C4 alkoxy, hydroxy, nitro or amino, benzyl, pyridyl or C1-C6 alkoxycarbonyl, is saponified with hydrochloric acid at a temperature of 120-160 ° C and at a pressure of 0.3-0.6 MPa (overpressure), in the presence of an inert organic solvent that is immiscible with water. |
| priorityDate | 1999-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.