| abstract |
The present invention relates to a liquid composition having the improved stability comprising a pharmaceutical asset, a solvent to solubilize the aforementioned asset, and a reducing agent to improve the stability of the aforementioned asset in the aforementioned composition, wherein the mentioned reducing agent is selected from the group consisting of the metabisulfite and bisulfite salts, including its sodium and potassium salts; dithiothreitol; thiourea; sodium thiosulfate; thioglycolic acid; tert-butyl hydroquinone (TBHQ); acetyl-cysteine; hydroquinone and mixtures thereof and wherein said reducing agent comprises from 0.005% to 1,000%, of the composition and method for its application. |