abstract |
A compound of the formula (I): <EMI FILE = "99050691_1" ID = "1" MFI = JPEG> characterized in that Z represents a 5 or 6 membered cycloalkyl, aryl, substituted cycloalkyl, or substituted aryl, said cycloalkyl, aryl , substituted cycloalkyl, or substituted aryl optionally contains one or more heteroatoms selected from 0, N, or S; R1 represents hydrogen or methyl; R2 represents hydrogen, C1-12 alkyl, aryl or aralkyl; k represents O or 1; n represents an integer from 1 to 50; X represents -O-, -N (H) -, -N (C1-6 alkyl) - -N (C3-8 cycloalkyl) -, -N (C1-8 alkyl) (C3-8 cycloalkyl), -N [( CH2CH2O) m (C1-12 alkyl, aryl or aralkyl)] -, -CH2O-, -CH2NH-, -CH2N (C1-6 alkyl) -, -CH2N (C3-8 cycloalkyl) -, or -C1 alkyl -12-. m represents 0-12; Q represents (-CH2) p, (-CH = CH-) p, (-C = C-) p, (- (O) P1CH2-) p or (-CH2 (0) P1) P where p and p1 independently represent an integer from O to 4; yey 'independently represent integers from O to 10; R3 represents H, straight or branched C1-12 alkyl (optionally substituted by phenyl, phenyl -CO-, CN, -CO alkyl (C1-3) -C02 (C1-3) alkyl, which contains one or more atoms or in the alkyl chain); straight or branched C1-6 alkenyl chain (optionally substituted by phenyl, phenyl -CO-, CN, -Calkyl -CO (C1-3), -C02 (C1-3) alkyl, or containing one or more atoms or in the alkyl chain); straight or branched chain alkenyl with C1-6 straight or branched chain alkynyl with C1-6 or a C1-3-NR8R9 -alkyl group where R8 and R9 are independently H, C1-3alkyl or together form a heterocyclic group with 5 or 6 members, optionally containing other heteroatoms selected from O, N or S; R4 and R5 independently represent -C3-8 alkyl-straight or branched C1-6 alkyl-hydrogen-alkenyl with C2-6 chain straight or branched-aryl or substituted aryl; -heterocyclic group or substituted heterocyclic group, which includes heteroaryl and substituted heteroaryl groups; R6 and R7 independently represent 0 or S; with the proviso that when -yey´ both represent 1, -k represents 1, -p1 represents zero, -R2 represents H or Me, -R3 represents H, -X represents 0 or NH, and Z represents phenylR4 and R5 both do not represent cyclohexyl; or a solvate of it. |