http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-5050293-A1

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filingDate 2000-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10025aaeba4ab097b2c2cf28e20d1fab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a91aede18f55dfbbcb0e616a1da81e92
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publicationDate 2001-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CO-5050293-A1
titleOfInvention REPLACED BISINDOLILMALEIMIDAS
abstract A compound having the formula and its pharmaceutically acceptable salts of said compounds, wherein: R is selected from the group consisting of -PO3 R1 R2, -CHR3 OCOR4, -CHR3 OCO2 R4, -CHR3 OCONHR4 and -COR4; R1 and R2 are chosen from the group consisting of H, Na and NH4, and are equal unless R1 or R2 is H, in which case the other may be different, or alternatively, R1 and R2 together represent Ca; R3 is chosen from group consisting of H or methyl; R4 is selected from the group consisting of lower alkyl, which may be optionally substituted by one or more substituents chosen from the group consisting of -CO2 R5, -NR6 R7, polyethylene glycol, -OPO3 R1 R2, hydroxyl, alkoxy and aryl, alquelino, which may be optionally substituted by one or more substituents chosen from the group consisting of -CO2 R5, -NR6 R7, polyethylene glycol, -OPO3 R1 R2, hydroxy, alkoxy and aryl, cycloalkyl which may be optionally substituted by one or more substituents chosen from the group consisting of -CO2 R5, -NR6 R7, polyethylene glycol, -OPO3 R1 R2, hydroxyl, alkoxy and aryl, heterocycle, which when N is included as a hetero atom, N may optionally be substituted by -COR8, and aryl which may optionally be substituted by one or more substituents chosen from the group consisting of -CO2 R5, hydroxyl, alkoxy, polyethylene glycol, -OPO3 R1 R2, and alkyl which may itself be substituted by hydroxyl, carboxyl and substituted amino; R5 is chosen from the group consisting of H, Na, or lower alkyl, R6 and R7 are each independently selected from H, lower alkyl and -COR8, or alternatively, the group -NR6 R7 forms a 5- or 6-membered heterocyclic ring; and R8 is lower alkyl, which may optionally be substituted by a polyethylene glycol.
priorityDate 1999-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 33.