| abstract |
A compound of formula (3), or a pharmaceutically acceptable salt or derivative thereof, wherein: R1 is vinyl or ethyl; and R2 is a group R3, R4 CH2- or R5 R6 C = CH-; wherein each R3 and R4 is an azabicyclic ring system or R5 and R6, together with the carbon atom to which they are attached, form an azabacyclic ring system.A process for preparing a compound according to any of the preceding claims, which includes reacting a compound of formula (4), wherein X is hydrogen or a hydroxyl protecting group, or a compound of formula (5), with an acid isocyanate of formula R3 CONCO, R4 CH2 CONCO or R5 R6 C = CHCONCO: A method for treating microbial infections in animals, especially humans and domesticated mammals, comprising administering an antimicrobial effective amount of a compound according to claim 1, 2 or 3, or a composition according to claim 7, to a patient in need. |