http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-5021216-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 |
| filingDate | 1998-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f717c1d5723f53cb45e0a33478d1bc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08c8e0bd335c79f931bb71da16894dc7 |
| publicationDate | 2001-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CO-5021216-A1 |
| titleOfInvention | SELECTIVE CARPROPHENE FOR COX-2, FOR THE TREATMENT OF PAIN AND INFLAMMATION IN DOGS |
| abstract | Treatment or prevention of inflammatory processes or diseases in dogs associated with the activity of inducible cyclo-oxygenase-2 (COX-2), while at the same time reducing or eliminating undesirable side effects associated with the simultaneous inhibition of the activity of the constitutive cyclo-oxygenase-1 (COX-1), by selective inhibition of COX-2 activity with respect to COX-1 activity, where the selective ratio of COX-2: COX-1 is at least 3: 1 based on ex vivo inhibition levels measured in whole blood; the inhibitor is a member selected from the group of anti-inflammatory compounds consisting essentially of derivatives of salicylic acid; p-aminophenol derivatives; indole and indene acetic acids; heteroaryl acetic acid; arylpropionic acids; anthranilic acids; enolic acids; and alkanones; the inhibitor, in particular, is composed of the (+) (S) enantiomer of 6-chloro-a-methyl-9H-carbazol-2-acetic acid. |
| priorityDate | 1998-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.